SCYL1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8395-50, BS8395-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q96KG9

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF

All Applications: WB: 1:500~1:2000
IHC/IF: 1:50~1:200

Background: With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SCYL1 polyclonal antibody detects endogenous levels of SCYL1 protein.

Bioworld Molecular Weight: ~ 110 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry of paraffin-embedded human liver injury using SCYL1 antibody at dilution of 1:100 (x40 lens)., Immunohistochemistry of paraffin-embedded rat kidney using SCYL1 antibody at dilution of 1:100 (x40 lens)., Immunofluorescence analysis of MCF-7 cell using SCYL1 antibody. Blue: DAPI for nuclear staining., Western blot analysis of extracts of various cell lines, using SCYL1 Antibody.

Alternative Name: N-terminal kinase-like protein; Coated vesicle-associated kinase of 90 kDa; SCY1-like protein 1; Telomerase regulation-associated protein; Telomerase transcriptional element-interacting factor; Teratoma-associated tyrosine kinase; SCYL1; CVAK90; GKLP; NTKL; TAPK; TEIF; TRAP; HT019

Immunogen: Recombinant full length Human SCYL1.

Conjugate: Unconjugated

Modification: Unmodified