ASCL1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA22129-50, RA22129-100 Citations, Manuals and MSDS Available upon request. Background: achaete-scute family bHLH transcription factor 1 (ASCL1) Homo sapiens This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3') . Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: IHC-p 1:50-200, ELISA 1:10000-20000 Alternative Names: Achaete-scute homolog 1 (ASH-1;hASH1;Class A basic helix-loop-helix protein 46;bHLHa46) Applications: IHC-p; IF (paraffin section) ; ELISA Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 429 SWISS: P50553 Source: Rabbit Research Use Only