Artemis Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA22097-50, RA22097-100 Citations, Manuals and MSDS Available upon request. Background: DNA cross-link repair 1C (DCLRE1C) Homo sapiens This gene encodes a nuclear protein that is involved in V (D) J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. Alternative Names: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C; Protein artemis; DNA cross-link repair 1C protein; Protein A-SCID; SNM1 homolog C; hSNM1C; SNM1-like protein Applications: IHC-p; IF/ICC; ELISA Species Cross-Reactivity: Human; Rat; Mouse GeneID (Human): 64421 SWISS: Q96SD1 Source: Rabbit Research Use Only