HAP1 Polyclonal Antibody

Sizes: 100µl, 1ml

Catalogue Numbers: BS74040-100, BS74040-1ml

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Swiss-Prot: P54257

Host: Rabbit

Reactivity: Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: HAP1 polyclonal antibody detects endogenous levels of HAP1 protein.

Bioworld Molecular Weight: ~ 76 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of HAP1 polyclonal antibody at 1:1000 dilution.
Lysates/proteins: 25ug per lane.

Alternative Name: HAP1; HAP2; HIP5; HLP; hHLP1

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human HAP1.

Conjugate: Unconjugated

Modification: Unmodified