Benzyl-PEG5-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1807539-07-6

Molecular Weight: 406.49

Formula: C18H30O8S

Chemical Name: 1-phenyl-2,5,8,11,14-pentaoxahexadecan-16-yl methanesulfonate

Smiles: CS(=O)(=O)OCCOCCOCCOCCOCCOCC1C=CC=CC=1

InChiKey: ILKVVAFIJJSDHU-UHFFFAOYSA-N

InChi: InChI=1S/C18H30O8S/c1-27(19,20)26-16-15-24-12-11-22-8-7-21-9-10-23-13-14-25-17-18-5-3-2-4-6-18/h2-6H,7-17H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.