ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels.

Product information

CAS Number: 1023043-30-2

Molecular Weight: 411.93

Formula: C17H18ClN3O3S2

Chemical Name: 8-[(5-chlorothiophen-2-yl)sulfonyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one

Smiles: O=C1NCN(C2C=CC=CC=2)C21CCN(CC2)S(=O)(=O)C1=CC=C(Cl)S1

InChiKey: RYWWSVHLSVFIIG-UHFFFAOYSA-N

InChi: InChI=1S/C17H18ClN3O3S2/c18-14-6-7-15(25-14)26(23,24)20-10-8-17(9-11-20)16(22)19-12-21(17)13-4-2-1-3-5-13/h1-7H,8-12H2,(H,19,22)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 5 mg/mL (12.14 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ATP synthase inhibitor 1 (Compound 10) is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex.

Products are for research use only. Not for human use.