TNFSF14 Polyclonal Antibody

Catalogue Numbers: BS61000-50, BS61000-100

Sizes: 50µl, 100µl

Alternative Name: Tumor necrosis factor ligand superfamily member 14; Herpes virus entry mediator ligand; HVEM-L; Herpesvirus entry mediator ligand; CD258; Cleaved into the following 2 chains; Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form; TNFSF14; HVEML; LIGHT; UNQ391; PRO726

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O43557

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Herpes virus entry mediator (HVEM), a type I transmembrane protein, is a member of the TNF receptor superfamily. HVEM mediates the entry of herpes simplex virus (HSV) 1 and 2 into T lymphocytes by serving as an attachment site for the HSV envelope glycoprotein D (gD). HVEM also binds two cellular ligands, secreted lymphotoxin α and light. LIGHT is a member of the TNF superfamily produced by activated T cells. This type II transmembrane protein competes with HSV glycoprotein D for binding to HVEM. LIGHT is closely related in sequence to lymphotoxin β (LTβ) and can also bind to the LTβ receptor. LIGHT is also known to induce apoptosis and suppress tumor formation.The gene encoding LIGHT maps to human chromosome 19p13.3.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TNFSF14 polyclonal antibody detects endogenous levels of TNFSF14 protein.

Bioworld Molecular Weight: ~ 26 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of TNFSF14 polyclonal antibody at 1:500
Line1:Hela whole cell lysate
Line2:Raw264.7 whole cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human TNFSF14.

Conjugate: Unconjugated

Modification: Unmodified