FAP Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS66158-50, BS66158-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q12884

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IF/ICC

All Applications: IF/ICC: 1:50-1:200

Background: The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FAP polyclonal antibody detects endogenous levels of FAP protein.

Bioworld Molecular Weight: ~ 90 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunofluorescence analysis of A-549 cells using FAP pAb at dilution of 1:100 (40x lens)., Immunofluorescence analysis of 3T3-L1 cells using FAP pAb at dilution of 1:100 (40x lens)., Immunofluorescence analysis of PC12 cells using FAP pAb at dilution of 1:100 (40x lens).

Alternative Name: FAP; DPPIV; FAPA; FAPalpha; SIMP

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-760 of human Fibroblast activation protein-α (FAP) (NP_004451.2).

Conjugate: Unconjugated

Modification: Unmodified