Cytokeratin 13 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2124-50, ES2124-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008],

Alternate Name: KRT13; Keratin; type I cytoskeletal 13; Cytokeratin-13; CK-13; Keratin-13; K13

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Cytokeratin 13. AA range:233-282

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 52kD

Human Gene ID: 3860

Human SWISS Prot NO: P13646

Subcellular Location: nucleus, intermediate filament, keratin filament, intermediate filament cytoskeleton, extracellular exosome,

Research Use Only