Recombinant Human INPP5A Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH033170-10, PKSH033170-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: INPP5A

Target Synonym: Type I inositol 1,4,5-trisphosphate 5-phosphatase; INPP5A

UNIProt ID: Q14642

Research Areas: Signal Transduction;

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-6His

Accession: Q14642

Background: Type I inositol 1, 4, 5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1, 4, 5-trisphosphate 5-phosphatase type I family. Type I inositol-1, 4, 5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1, 4, 5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.

Sequence: Met 1-Val410

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 48.5 kDa

Observed MW: 45 kDa

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Research Use Only