KVβ1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20681-50, ES20681-100

Citations, Manuals and MSDS Available upon request.

Background: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alp

Alternate Name: Voltage-gated potassium channel subunit beta-1 (K (+) channel subunit beta-1; Kv-beta-1)

Source: Rabbit

Applications: IHC; IF

Dilution: IHC 1:100-200

Reactivity: Human; Rat; Mouse

Immunogen: Synthetic Peptide of KVβ1 AA range: 66-116

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 50kD

Human Gene ID: 7881

Human SWISS Prot NO: Q14722

Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Recruited to the cytoplasmic side of the cell membrane via its interaction with pore-forming potassium channel alpha subunits.

Research Use Only