PK1IP rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES10732-50, ES10732-100

Citations, Manuals and MSDS Available upon request.

Background: function:Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42., similarity:Contains 5 WD repeats., subunit:Interacts with PAK1., tissue specificity:Expressed in brain, colon, heart, kidney, liver, lung, muscle, peripheral blood leukocytes, placenta, small intestine, spleen and thymus.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 43kD

Human Gene ID: 55003

Human SWISS Prot NO: Q9NWT1

Subcellular Location: Nucleus, nucleolus.

Research Use Only