RPL22 Polyclonal Antibody

Catalogue Numbers: BS61113-50, BS61113-100

Sizes: 50µl, 100µl

Alternative Name: 60S ribosomal protein L22; EBER-associated protein; EAP; Epstein-Barr virus small RNA-associated protein; Heparin-binding protein HBp15; RPL22

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P35268

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Ribosomal Protein L22 is also known as heparin-binding protein HBp15, because it binds heparin in the submandibular gland and brain. This small protein is also associated with two small nuclear RNAs called EBERs (Epstein- Barr encoded RNAs). These RNAs are synthesized in large amounts by human B lymphocytes infected with Epstein-Barr virus (EBV). Ribosomal protein L22, like L4, contains a globular domain that sits on the surface of the large ribosomal subunit and an extended loop that penetrates its core. These extensions contact multiple domains of 23S rRNA, indicating a potential, but not essential, role in rRNA folding during ribosomal assembly.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RPL22 polyclonal antibody detects endogenous levels of RPL22 protein.

Bioworld Molecular Weight: ~ 15 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Ribosomal Protein L22 (L91) pAb at 1:500 dilution
Lane 1: CT26 whole cell lysate(40ug)
Lane 2: Myla2059 whole cell lysate(30ug)
Lane 3: A2780 whole cell lysate(40ug)

Immunogen: A synthetic peptide corresponding to residues in Human RPL22.

Conjugate: Unconjugated

Modification: Unmodified