CDH13 (M352) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2219-50, BS2219-100

Sizes: 50µl, 100µl

Swiss-Prot: P55290

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF

Background: The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. T-cadherin (for truncated-cadherin, also designated heartcadherin or cadherin-13) expression levels have been shown to be reduced in human breast cancers and carcinoma cells lines. Evidence suggests that

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CDH13 (M352) polyclonal antibody detects endogenous levels of CDH13 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of CDH13 (M352) polyclonal antibody at 1:500 dilution
Lane 1: Hela whole cell lysate (40ug)
Lane 2: H9C2 whole cell lysate (40ug)
Lane 3: NIH-3T3 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of CDH13 (M352) pAb in paraffin-embedded human tonsil cancer tissue at 1:50.

Bioworld Molecular Weight: 78,105,130kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: CAD13; Cadherin-13; CDH13; CDHH; H-cadherin; Heart Cadherin; P105; T cad; T Cadherin; T-cad; T-cadherin; Truncated Cadherin;

Immunogen: Synthetic peptide, corresponding to amino acids 330-380 of Human CDH13.

Conjugate: Unconjugated

Modification: Unmodified