SIGLEC5 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-14839-60, E-AB-14839-120, E-AB-14839-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: SIGLEC5

Target Synonym: CD170; CD170 antigen; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OB-BP2; OBBP2; Obesity-binding protein 2; Sialic acid binding Ig-like lectin 5; Sialic acid binding immunoglobulin-like lectin 5; Sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; SIGL5; Siglec-5; Siglec-F variant; Siglec5; Siglecf

Research Areas: Cancer, Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O15389

Background: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human SIGLEC5

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Calculated MW: 61kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only