BNIP1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90142-50, BS90142-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q12981(Human) Q8VHI8(Rat)

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, ICC IHC

All Applications: WB:1:500
ICC:1:50-1:200
IHC:1:50-1:100

Background: The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria.

Purification and Purity: ProA affinity purified.

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: BNIP1 polyclonal antibody detects endogenous levels of BNIP1 protein.

Bioworld Molecular Weight: 26 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of BNIP1 on rat liver tissue lysate using anti-BNIP1 antibody at 1/500 dilution., ICC staining BNIP1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: TRG-8, BNIP1, NIP1, SEC20L, BCL2 adenovirus E1B 19kD interacting protein 1, BCL2/adenovirus E1B 19 kDa protein-interacting protein 1, BNIP1, MGC41600, Nip1, OTTHUMP00000161077, OTTHUMP00000161078, OTTHUMP00000161079, OTTHUMP00000223580, sec20, SEC20, SEC20L, Transformation-related gene 8 protein, TRG-8, TRG8, Vesicle transport protein SEC20,

Immunogen: Recombinant protein with human BN1P1 aa 1-220.

Conjugate: Unconjugated

Modification: Unmodified