TAT-amide TFA is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells.

Product information

Molecular Weight: 1672.87

Formula: C66H120F3N33O15

Chemical Name: (S)-2-((2S, 5S, 8S, 11S, 14S, 20S)-20-amino-8, 11-bis(4-aminobutyl)-2, 5, 14-tris(3-guanidinopropyl)-21-(4-hydroxyphenyl)-4, 7, 10, 13, 16, 19-hexaoxo-3, 6, 9, 12, 15, 18-hexaazahenicosanamido)-N1-((6S, 9S, 12S)-1, 17-diamino-6-carbamoyl-9-(3-guanidinopropyl)-1, 17-diimino-8, 11-dioxo-2, 7, 10, 16-tetraazaheptadecan-12-yl)pentanediamide 2, 2, 2-trifluoroacetate

Smiles: N[C@@H](CC1C=CC(O)=CC=1)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O.OC(=O)C(F)(F)F

InChiKey: VISIBNLMWGWWOW-VNBTWCPKSA-N

InChi: InChI=1S/C64H119N33O13.C2HF3O2/c65-25-3-1-11-40(91-51(103)39(14-6-28-83-60(72)73)89-48(100)34-88-50(102)37(67)33-35-19-21-36(98)22-20-35)53(105)92-41(12-2-4-26-66)54(106)94-43(16-8-30-85-62(76)77)55(107)95-45(18-10-32-87-64(80)81)57(109)97-46(23-24-47(68)99)58(110)96-44(17-9-31-86-63(78)79)56(108)93-42(15-7-29-84-61(74)75)52(104)90-38(49(69)101)13-5-27-82-59(70)71;3-2(4,5)1(6)7/h19-22,37-46,98H,1-18,23-34,65-67H2,(H2,68,99)(H2,69,101)(H,88,102)(H,89,100)(H,90,104)(H,91,103)(H,92,105)(H,93,108)(H,94,106)(H,95,107)(H,96,110)(H,97,109)(H4,70,71,82)(H4,72,73,83)(H4,74,75,84)(H4,76,77,85)(H4,78,79,86)(H4,80,81,87);(H,6,7)/t37-,38-,39-,40-,41-,42-,43-,44-,45-,46-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

CPPs have been employed in cellular delivery of cargoes such as DNA, siRNA, organic halide, ruthenium complex, Zr-labeled antibody for PET imaging, low-molecular-weight chitosan, and fluorescent dyes.

Products are for research use only. Not for human use.