BNP Rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20876-50, ES20876-100

Citations, Manuals and MSDS Available upon request.

Background: Natriuretic peptide B (NPPB) Homo sapiens This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.

Alternate Name: Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)

Source: Rabbit

Applications: IHC

Dilution: IHC 1:50-200

Reactivity: Human

Immunogen: Synthesized peptide derived from human BNP AA range: 89-139

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 37kD

Human Gene ID: 64223

Human SWISS Prot NO: Q9BVC4

Subcellular Location: Cytoplasm

Research Use Only