ECE2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16986-60, E-AB-16986-120, E-AB-16986-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ECE2

Target Synonym: ECE 2; ECE-2; ECE2; ECE2; Endothelin converting enzyme 2; Endothelin-converting enzyme 2 region; Hypothetical protein MGC2408; KIAA0604; MGC17664; MGC78487

Research Areas: Cardiovascular, Neuroscience, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O60344

Background: This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants.

Concentration: 0.4 mg/mL

Immunogen: Fusion protein of human ECE2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-2000, IHC 1:30-150, ELISA 1:2000-5000

Calculated MW: 100 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only