UBP310 is a selective GluR5 antagonist, with a Kd of 130 nM.

Product information

CAS Number: 902464-46-4

Molecular Weight: 353.35

Formula: C14H15N3O6S

Chemical Name: 3-({3-[(2S)-2-amino-2-carboxyethyl]-5-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-1-yl}methyl)thiophene-2-carboxylic acid

Smiles: CC1=CN(C[C@H](N)C(O)=O)C(=O)N(CC2C=CSC=2C(O)=O)C1=O

InChiKey: ZTAZUCRXCRXNSU-VIFPVBQESA-N

InChi: InChI=1S/C14H15N3O6S/c1-7-4-16(6-9(15)12(19)20)14(23)17(11(7)18)5-8-2-3-24-10(8)13(21)22/h2-4,9H,5-6,15H2,1H3,(H,19,20)(H,21,22)/t9-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

UBP310 binds to GluR5 S1S2 with an affinity of 130 nM and shows 12,700-fold selectivity for GluR5 versus GluR6 and 830-fold selectivity for GluR5 versus GluR2.

Products are for research use only. Not for human use.