BACE2 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA31257-50, RA31257-100 Citations, Manuals and MSDS Available upon request. Background: beta-site APP-cleaving enzyme 2 (BACE2) Homo sapiens This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000 Applications: WB; ELISA Species Cross-Reactivity: Human; Rat; Mouse GeneID (Human): 25825 Protein MW (KDa): 56 SWISS: Q9Y5Z0 Source: Rabbit Research Use Only