CA IX/Carbonic Anhydrase IX Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1076-50, EM1076-100

Citations, Manuals and MSDS Available upon request.

Background: The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of the best cellular biomarkers of hypoxia. Furthermore, recent studies examining the association between CAIX levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of hypoxic regions in many solid tumors.

Alternate Name: CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, carbonic anhydrase IX, G250, Membrane antigen MN, MN, P54/58N, pMW1, RCC associated antigen G250

Source: Mouse

Applications: WB, IHC, IP

Dilution: WB 1:3, 000 IP 1:200  IHC 1:100-200

Reactivity: Human

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 35-38kDa

Human Gene ID: 768

Human SWISS Prot NO: Q16790

Subcellular Location: Nucleus. Nucleus, nucleolus. Cell membrane. Cell projection, microvillus membrane.

Research Use Only