Recombinant Rat IL-4 Protein

Sizes: 20μg, 100μg

Catalogue Numbers: PDMR100003-20, PDMR100003-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: IL-4

Target Synonym: Interleukin-4; IL4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra

UNIProt ID: P20096

Research Areas: Cancer; Cardiovascular; Immunology;

Target Species: Rat

Expression Host: HEK293 Cells

Fusion Tag: C-His

Accession: P20096

Background: Participates in at least several B-cell activation processes as well as of other cell types.
It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.
Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.

Sequence: Met1-Ser147

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: Please contact us for more information.

Calculated MW: 16.5 kDa

Observed MW: 17 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only