NDE1 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS8718-50, BS8718-100

Swiss-Prot: Q9NXR1

Host: Rabbit

NDE1 Polyclonal Antibody-BS8718

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse

Applications: WB, IF

All Applications: WB: 1:500~1:2000
IF: 1:50~1:200

Background: This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: NDE1 polyclonal antibody detects endogenous levels of NDE1 protein.

Bioworld Molecular Weight: ~ 39kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using NDE1 antibody., Immunofluorescence analysis of A549 cell using NDE1 antibody. Blue: DAPI for nuclear staining.

Alternative Name: Nuclear distribution protein nudE homolog 1; NudE; NDE1; NUDE

Immunogen: Recombinant full length Human NDE1.

Modification: Unmodified

Conjugate: Unconjugated