MDH2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8109-50, BS8109-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P40926

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC

All Applications: WB: 1:500~1:2000
IHC: 1:50~1:200

Background: MDH2 (malate dehydrogenase, NAD mitochondrial), also known as MDH, MOR1 or M-MDH, is a 338 amino acid that belongs to the LDH/MDH superfamily. MDH2 localizes to the mitochondria and may play a critical role in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. MDH2 utilizes the NAD/NADH cofactor system in the citric acid cycle to catalyze the reversible oxidation of malate to oxaloacetate. Oxaloacetate is involved in many important metabolic pathways including amino acid synthesis, gluconeogenesis and facilitation of the exchange of metabolites between cytoplasm and subcellular organelles.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MDH2 polyclonal antibody detects endogenous levels of MDH2 protein.

Bioworld Molecular Weight: ~ 36 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot (WB) analysis of MDH2 polyclonal antibody

Alternative Name: Malate dehydrogenase; mitochondrial; MDH2

Immunogen: Recombinant full length Human MDH2.

Conjugate: Unconjugated

Modification: Unmodified