Bcl-6 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA22351-50, RA22351-100

Citations, Manuals and MSDS Available upon request.

Background: B-cell CLL/lymphoma 6 (BCL6) Homo sapiens The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: BCL6; BCL5; LAZ3; ZBTB27; ZNF51; B-cell lymphoma 6 protein; BCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51

Applications: IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 604

SWISS: P41182

Source: Rabbit

Research Use Only