IDO inhibitor 1 is a potent and novel indoleamine-2,3 dioxygenase (IDO) inhibitor with IC50 value <100 nM. IDO is an enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine and permits tumor cells to escape the immune system.

Product information

CAS Number: 1204669-37-3

Molecular Weight: 438.23

Formula: C11H13BrFN7O4S

Chemical Name: (E)-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-{[2-(sulfamoylamino)ethyl]amino}-1,2,5-oxadiazole-3-carboximidamide

Smiles: NS(=O)(=O)NCCNC1=NON=C1/C(/NO)=N\C1C=C(Br)C(F)=CC=1

InChiKey: FBKMWOJEPMPVTQ-UHFFFAOYSA-N

InChi: InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.