Recombinant Rat Interleukin-2/IL-2 Protein (His Tag)

Sizes: 20μg, 100μg

Catalogue Numbers: PDMR100011-20, PDMR100011-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: Interleukin-2; IL-2

Target Synonym: Aldesleukin; IL 2; IL-2; IL2; IL2; Interleukin 2; Interleukin-2; Involved in regulation of T cell clonal expansion; Lymphokine; POIL2; T Cell Growth Factor; T-cell growth factor; TCGF

UNIProt ID: P17108

Research Areas: Signal Transduction;; immunology

Target Species: Rat

Expression Host: HEK293 Cells

Fusion Tag: C-His

Accession: P17108

Background: Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2, respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.

Sequence: Ala 21-Gln 155

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: Please contact us for more information.

Calculated MW: 14.74 kDa

Observed MW: 16 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only