AIMP1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53139-60, E-AB-53139-120, E-AB-53139-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: AIMP1

Target Synonym: AIMP 1; Aimp1; AIMP1/p43; AIMP1; Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; ARS interacting multifunctional protein 1; EMAP 2; EMAP-2; EMAP-II; EMAP2; EMAPII; Endothelial monocyte activating polypeptide 2; Endothelial monocyte activating polypeptide; Endothelial monocyte-activating polypeptide 2; Endothelial monocyte-activating polypeptide II; HLD3; Multisynthase complex auxiliary component p43; Multisynthetase complex auxiliary component p43; OTTHUMP00000219673; p43; Scye 1; Scye1; Scye1; formerly; Small inducible cytokine subfamily E member 1; Small inducible cytokine subfamily E; member 1 (endothelial monocyte-activating); Small inducible cytokine subfamily E; member 1; formerly

Research Areas: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Immunology, Tags and Cell Markers

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q12904

Background: The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.

Concentration: 1.2 mg/mL

Immunogen: Fusion protein of human AIMP1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only