NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM; no activities on NR2A, NR2C, NR2D, hERG-channel and α1-adrenergic receptor.

Product information

CAS Number: 700878-19-9

Molecular Weight: 412.33

Formula: C20H24Cl2FN3O

Chemical Name: 2-({4-[(2-fluorophenyl)methyl]piperidin-1-yl}methyl)-1H-1,3-benzodiazol-6-ol dihydrochloride

Smiles: Cl.Cl.OC1=CC2NC(CN3CCC(CC4=CC=CC=C4F)CC3)=NC=2C=C1

InChiKey: JYUWGWCFJMDMND-UHFFFAOYSA-N

InChi: InChI=1S/C20H22FN3O.2ClH/c21-17-4-2-1-3-15(17)11-14-7-9-24(10-8-14)13-20-22-18-6-5-16(25)12-19(18)23-20;;/h1-6,12,14,25H,7-11,13H2,(H,22,23);2*1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 12.5 mg/mL (33.26 mM; ultrasonic and warming and heat to 60°C).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

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