VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM.

Product information

CAS Number: 1222810-74-3

Molecular Weight: 368.30

Formula: C16H12N6O5

Chemical Name: 6-nitro-2-{[(6-nitro-1H-1,3-benzodiazol-2-yl)methoxy]methyl}-1H-1,3-benzodiazole

Smiles: [O-][N+](=O)C1=CC2NC(COCC3NC4C=C(C=CC=4N=3)[N+]([O-])=O)=NC=2C=C1

InChiKey: ZQPXNYLXYNRFNP-UHFFFAOYSA-N

InChi: InChI=1S/C16H12N6O5/c23-21(24)9-1-3-11-13(5-9)19-15(17-11)7-27-8-16-18-12-4-2-10(22(25)26)6-14(12)20-16/h1-6H,7-8H2,(H,17,19)(H,18,20)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 62.5 mg/mL (169.70 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.