AChRα3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21603-50, RA21603-100

Citations, Manuals and MSDS Available upon request.

Background: cholinergic receptor nicotinic alpha 3 subunit (CHRNA3) Homo sapiens This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: CHRNA3; NACHRA3; Neuronal acetylcholine receptor subunit alpha-3

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 1136

Protein MW (KDa): 57

SWISS: P32297

Source: Rabbit

Research Use Only