Recombinant Human RAB38 protein (His tag)

Size: 100μg

Catalogue Numbers: PDEH100349-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: RAB38

Target Synonym: RAB38; Ras-related protein Rab-38; Melanoma antigen NY-MEL-1

UNIProt ID: P57729

Research Areas: Signal Transduction

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His & C-His

Accession: P57729

Background: May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity).
Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211).
Plays an important role in the control of melanin production and melanosome biogenesis (PubMed:23084991).
In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).

Sequence: Met 1-Ser 211

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: Please contact us for more information.

Calculated MW: 23.1 kDa

Observed MW: 29 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only