BIBO 3304 Trifluoroacetate (BIBO-3304 TFA) is a novel neuropeptide Y Y1 receptor (NPY1R) antagonist with IC50 values of 0.38 nM and 0.72 nM for human Y1 receptor and rat Y1 receptor, respectively. BIBO 3304 shows low affinity for the human Y2 receptor, human and rat Y4 receptor as well as for the human and rat Y5 receptor (IC50 values >1000 nM).

Product information

CAS Number: 191868-14-1

Molecular Weight: 643.66

Formula: C31H36F3N7O5

Chemical Name: (2R)-5-carbamimidamido-N-({4-[(carbamoylamino)methyl]phenyl}methyl)-2-(2, 2-diphenylacetamido)pentanamide; trifluoroacetic acid

Smiles: NC(=O)NCC1=CC=C(CNC(=O)[C@@H](CCCNC(N)=N)NC(=O)C(C2C=CC=CC=2)C2C=CC=CC=2)C=C1.OC(=O)C(F)(F)F

InChiKey: FBMCYYWIBYEOST-GJFSDDNBSA-N

InChi: InChI=1S/C29H35N7O3.C2HF3O2/c30-28(31)33-17-7-12-24(26(37)34-18-20-13-15-21(16-14-20)19-35-29(32)39)36-27(38)25(22-8-3-1-4-9-22)23-10-5-2-6-11-23;3-2(4,5)1(6)7/h1-6,8-11,13-16,24-25H,7,12,17-19H2,(H,34,37)(H,36,38)(H4,30,31,33)(H3,32,35,39);(H,6,7)/t24-;/m1./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C). DMSO: 100 mg/mL(155.36 mM). Water: Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.