2-O-methyl-PAF C-18 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. It has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart. In rat astrocytes, 2-O-methyl PAF C-18 causes the release of large quantities of nitric oxide by a pathway involving activation of nitric oxide synthase.

Product information

CAS Number: 77286-66-9

Molecular Weight: 523.73

Formula: C27H58NO6P

Chemical Name: (2S)-2-methoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate

Smiles: CO[C@@H](COCCCCCCCCCCCCCCCCCC)CO[P@]([O-])(=O)OCC[N+](C)(C)C

InChiKey: MHFRGQHAERHWKZ-MHZLTWQESA-N

InChi: InChI=1S/C27H58NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-32-25-27(31-5)26-34-35(29,30)33-24-22-28(2,3)4/h27H,6-26H2,1-5H3/t27-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.