PSN632408 is a potent and selective agonist of GPR119 receptors that shows similar potency to OEA at both recombinant mouse and human GPR119 receptors, exhibiting EC50 values of 5.6 and 7.9 µM, respectively (EC50 values for OEA are 3.2 and 2.9 µM, respectively). OEA and PSN632408 can stimulate β-cell replication in vitro and in vivo and improve islet graft function. PSN632408 is potential useful for treatment of diabetics.

Product information

CAS Number: 857652-30-3

Molecular Weight: 360.41

Formula: C18H24N4O4

Synonym:

PSN 632408

PSN-632408

Chemical Name: tert-butyl 4-{[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]methoxy}piperidine-1-carboxylate

Smiles: CC(C)(C)OC(=O)N1CCC(CC1)OCC1=NC(=NO1)C1=CC=NC=C1

InChiKey: LHZWKWCEAXQUMX-UHFFFAOYSA-N

InChi: InChI=1S/C18H24N4O4/c1-18(2,3)25-17(23)22-10-6-14(7-11-22)24-12-15-20-16(21-26-15)13-4-8-19-9-5-13/h4-5,8-9,14H,6-7,10-12H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.